Faculty Mentors - REU Site: Modeling and Simulation in Systems Biology (MSSB)
Faculty Mentors

Stefan Hoops
is a senior project associate at the Virginia Bioinformatics Institute. He earned his Ph.D. in Mathematical Physics from the Norwegian Institute of Technology in 1993. Before joining VBI in 2000, Hoops served as a software designer/developer for Schumann Consulting Corporation in Germany from 1995-2000. He was elected in 2006 as one of the 5 editors of the Systems Biology Markup Language (SBML), serving for the years 2007-2009.
At VBI, Hoops works with Dr. Pedro Mendes in the Biochemical Networks Modeling Group. The research group is interested in understanding how cells work at the biochemical level. Their approach can be labeled as Systems Biology, as they derive quantitative dynamic models from integrative functional genomic data. They have ongoing projects in development of methodologies and software for the complete process of going from functional genomic data to computational models: biochemical simulators (Gepasi and COPASI), database design (DOME and B-Net), data analysis, network inference, parameter estimation for nonlinear models, and theoretical aspects of biochemical regulation (such as Metabolic Control Analysis).

Reinhard Laubenbacher
is a professor at VBI, professor of mathematics in the VT Mathematics Department, and a faculty member in the interdepartmental Ph.D. program "Genetics, Bioinformatics, and Computational Biology (GBCB)." He also holds an adjunct faculty position in the Wake Forest University Department of Cancer Biology. Dr. Laubenbacher conducts research in modeling and simulation of biological networks, computational immunology, and bioinformatics tool development. For the last 15 years the PI has been involved in innovative projects in undergraduate research and education.

Christopher Lawrence
is an associate professor at the Virginia Bioinformatics Institute and associate professor in Virginia Tech's Department of Biological Sciences. He is also a faculty member of both the Inflammation and Biobased Materials and Design Processing Groups affiliated with the Institute for Critical Technology and Applied Sciences (ICTAS) at Virginia Tech. He received his Ph.D. in plant pathology and molecular biology from Auburn University in 1998. Prior to joining VBI in 2003, Lawrence served as an assistant professor of Molecular Biology and Genomics at Colorado State University, the director of a Plant Disease Resistance Biotechnology Program at the University of Kentucky, and as a visiting scholar in the Netherlands.

Pedro Mendes
Dr. Mendes' research at VBI is centered broadly around computer simulation and analysis of biochemical networks. This is comprised of three components: development of simulation software (Gepasi and now COPASI), modeling of gene expression in the context of metabolic networks, and bioinformatic support for metabolomics.

Dr. Mendes is the author of the popular biochemical simulation software Gepasi. This allows biochemists to model biochemical networks without having to write the mathematics explicitly (the program does that internally). Gepasi is thus targeted at those biochemists that need to do simulation but cannot spend time programming. More recently Dr. Mendes is engaged in collaboration with Dr. Ursula Kummer of EML Research, which has resulted in a new simulator called COPASI, which is the natural successor to Gepasi.

Suzy Torti
is Professor or Biochemistry at Wake Forest University in Winston-Salem, North Carolina. Dr. Torti's research interests include molecular biology/molecular me, information sciences, cancer/oncogenesis, cell growth, differentiation, statistics/mathematics, medical technology/devices, biotechnology.

For a list of recent publications by Dr. Torti, please click here.

2013 Program Dates: May 28 - August 3
Application deadline is February 4, 2013.


REU Site: MSSB is funded by NSF Award Number 1062878